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References
Rakic, P. & Caviness, V. S., Jr. Cortical development: view from neurological mutants two decades later. Neuron 14, 1101–1104 (1995)
Sentürk, A., Pfennig, S., Weiss, A., Burk, K. & Acker-Palmer, A. Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration. Nature 472, 356–360 (2011)
Xu, N. J. & Henkemeyer, M. Ephrin reverse signaling in axon guidance and synaptogenesis. Semin. Cell Dev. Biol. 23, 58–64 (2012)
Bouché, E. et al. Reelin induces EphB activation. Cell Res. 23, 473–490 (2013)
Yokoyama, N. et al. Forward signaling mediated by ephrin-B3 prevents contralateral corticospinal axons from recrossing the spinal cord midline. Neuron 29, 85–97 (2001)
Villar-Cerviño, V. et al. Contact repulsion controls the dispersion and final distribution of Cajal–Retzius cells. Neuron 77, 457–471 (2013)
Dahlstrand, J., Lardelli, M. & Lendahl, U. Nestin mRNA expression correlates with the central nervous system progenitor cell state in many, but not all, regions of developing central nervous system. Brain Res. Dev. Brain Res. 84, 109–129 (1995)
Insolera, R., Bazzi, H., Shao, W., Anderson, K. V. & Shi, S. H. Cortical neurogenesis in the absence of centrioles. Nat. Neurosci. 17, 1528–1535 (2014)
Thompson, C. L. et al. A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron 83, 309–323 (2014)
Xu, N. J. & Henkemeyer, M. Ephrin-B3 reverse signaling through Grb4 and cytoskeletal regulators mediates axon pruning. Nat. Neurosci. 12, 268–276 (2009)
Catchpole, T. & Henkemeyer, M. EphB2 tyrosine kinase-dependent forward signaling in migration of neuronal progenitors that populate and form a distinct region of the dentate niche. J. Neurosci. 31, 11472–11483 (2011)
Kullander, K. et al. Ephrin-B3 is the midline barrier that prevents corticospinal tract axons from recrossing, allowing for unilateral motor control. Genes Dev. 15, 877–888 (2001)
Xu, N. J., Sun, S., Gibson, J. R. & Henkemeyer, M. A dual shaping mechanism for postsynaptic ephrin-B3 as a receptor that sculpts dendrites and synapses. Nat. Neurosci. 14, 1421–1429 (2011)
Grunwald, I. C. et al. Hippocampal plasticity requires postsynaptic ephrinBs. Nat. Neurosci. 7, 33–40 (2004)
Rodenas-Ruano, A., Perez-Pinzon, M. A., Green, E. J., Henkemeyer, M. & Liebl, D. J. Distinct roles for ephrinB3 in the formation and function of hippocampal synapses. Dev. Biol. 292, 34–45 (2006)
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T.P., L.X., R.S. and A.B. performed experiments. H.H.B., M.H. and J.H. designed the experiments. T.P. and J.H. wrote the manuscript.
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Pohlkamp, T., Xiao, L., Sultana, R. et al. Ephrin Bs and canonical Reelin signalling. Nature 539, E4–E6 (2016). https://doi.org/10.1038/nature20129
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DOI: https://doi.org/10.1038/nature20129
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