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DNA repair

Telomere-lengthening mechanism revealed

Shortening of the ends of chromosomes limits a cell's lifespan. Some cancer cells avoid this fate through a mechanism called alternative lengthening of telomeres, molecular details of which have now been defined. See Article p.54

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Figure 1: Break-induced telomere synthesis.


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Correspondence to Steven E. Artandi.

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Roake, C., Artandi, S. Telomere-lengthening mechanism revealed. Nature 539, 35–36 (2016).

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