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Endothelial-cell killing promotes metastasis


To migrate into the lungs, cancer cells in the bloodstream must cross the lung's endothelial-cell barrier. A study shows that cancer cells can achieve this feat by signalling to induce endothelial-cell death. See Letter p.215

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Figure 1: Tumour cells migrate into tissues by killing cells that block their entry.


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Correspondence to Claudio R. Alarcón or Sohail F. Tavazoie.

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Alarcón, C., Tavazoie, S. Endothelial-cell killing promotes metastasis. Nature 536, 154–155 (2016).

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