Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Cell division

Mitotic regulation comes into focus

Structural studies provide insight into the mechanisms governing a checkpoint in cell division that prevents chromosomes from segregating before they are properly aligned on a structure called the mitotic spindle. See Article p.431

This is a preview of subscription content, access via your institution

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

Figure 1: Deciphering inhibition of cell division.

Notes

  1. See all news & views

References

  1. Musacchio, A. Curr. Biol. 25, R1002–R1018 (2015).

    CAS  Article  Google Scholar 

  2. Hoyt, M. A., Totis, L. & Roberts, B. T. Cell 66, 507–517 (1991).

    CAS  Article  Google Scholar 

  3. Li, R. & Murray, A. W. Cell 66, 519–531 (1991).

    CAS  Article  Google Scholar 

  4. Alfieri, C. et al. Nature 536, 431–436 (2016).

    ADS  CAS  Article  Google Scholar 

  5. Yamaguchi, M. et al. Mol. Cell http://dx.doi.org/10.1016/jmol.cel.2016.07.003 (2016).

  6. Primorac, I. & Musacchio, A. J. Cell Biol. 201, 177–189 (2013).

    CAS  Article  Google Scholar 

  7. Izawa, D. & Pines, J. Nature 517, 631–634 (2015).

    Google Scholar 

  8. Zhang, S. et al. Nature 533, 260–264 (2016).

    ADS  CAS  Article  Google Scholar 

  9. Yang, Q. & Ferrell, J. E. Jr Nature Cell Biol. 15, 519–525 (2013).

    Article  Google Scholar 

  10. Fujimitsu, K., Grimaldi, M. & Yamano, H. Science 352, 1121–1124 (2016).

    ADS  CAS  Article  Google Scholar 

  11. Qiao, R. et al. Proc. Natl Acad. Sci. USA 113, E2570–E2578 (2016).

    CAS  Article  Google Scholar 

  12. Valk, E. et al. Mol. Biol. Cell 25, 3456–3460 (2014).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to David O. Morgan.

Related links

Related links

Related links in Nature Research

Structural biology: A new look for the APC

Cell division: Hold on and let go

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Morgan, D. Mitotic regulation comes into focus. Nature 536, 407–408 (2016). https://doi.org/10.1038/nature19423

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nature19423

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing