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Heart disease

Death-defying plaque cells

Dead cells are usually removed through their ingestion and destruction by other cells. A study of plaque deposits in arteries shows that dying cells in plaques display a 'don't-eat-me' signal that blocks their removal. See Letter p.86

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Figure 1: Defective removal of dead cells can contribute to clinically dangerous atherosclerotic plaques.

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Correspondence to Ira Tabas.

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Tabas, I. Death-defying plaque cells. Nature 536, 32–33 (2016). https://doi.org/10.1038/nature18916

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