Figure 1: Ki-67 divides the crowd. | Nature

Figure 1: Ki-67 divides the crowd.

From: A sticky problem for chromosomes

Figure 1

During cell division, chromosomes, which are in the form of dense cylindrical units, separate from one another. Cuylen et al.1 report that chromosomes are kept apart by the protein Ki-67, which acts as a highly charged brush — one end binds to the chromosome and the positively charged protein extends into the cytoplasm, repelling other chromosomes. If Ki-67 is absent, chromosomes coalesce and cell division is delayed. (Adapted from ref. 1.)

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