This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Iatrogenic Creutzfeldt-Jakob disease with Amyloid-β pathology: an international study
Acta Neuropathologica Communications Open Access 08 January 2018
-
Amyloid-β accumulation in the CNS in human growth hormone recipients in the UK
Acta Neuropathologica Open Access 27 March 2017
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Get just this article for as long as you need it
$39.95
Prices may be subject to local taxes which are calculated during checkout
References
Jaunmuktane, Z. et al. Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy. Nature 525, 247–250 (2015)
Milner, R. D. et al. Experience with human growth hormone in Great Britain: the report of the MRC Working Party. Clin. Endocrinol. 11, 15–38 (1979)
Brown, P. et al. Iatrogenic Creutzfeldt–Jakob disease, final assessment. Emerg. Infect. Dis. 18, 901–907 (2012)
Buchanan, C. R., Preece, M. A. & Milner, R. D. Mortality, neoplasia, and Creutzfeldt-Jakob disease in patients treated with human pituitary growth hormone in the United Kingdom. Br. Med. J. 302, 824–828 (1991)
Buchanan, C. R., Law, C. M. & Milner, R. D. Growth hormone in short, slowly growing children and those with Turner’s syndrome. Arch. Dis. Child. 62, 912–916 (1987)
Rudge, P. et al. Iatrogenic CJD due to pituitary-derived growth hormone with genetically determined incubation times of up to 40 years. Brain 138, 3386–3399 (2015)
Nyberg, F. & Hallberg, M. Growth hormone and cognitive function. Nat. Rev. Endocrinol. 9, 357–365 (2013)
Webb, E. A. et al. Effect of growth hormone deficiency on brain structure, motor function and cognition. Brain 135, 216–227 (2012)
Falleti, M. G., Maruff, P., Burman, P. & Harris, A. The effects of growth hormone (GH) deficiency and GH replacement on cognitive performance in adults: a meta-analysis of the current literature. Psychoneuroendocrinology 31, 681–691 (2006)
Rose, S. R. & Auble, B. A. Endocrine changes after pediatric traumatic brain injury. Pituitary 15, 267–275 (2012)
Graham, D. I., Gentleman, S. M., Lynch, A. & Roberts, G. W. Distribution of beta-amyloid protein in the brain following severe head injury. Neuropathol. Appl. Neurobiol. 21, 27–34 (1995)
Westmark, C. J. What’s hAPPening at synapses? The role of amyloid β-protein precursor and β-amyloid in neurological disorders. Mol. Psychiatry 18, 425–434 (2013)
Carel, J. C. et al. Long-term mortality after recombinant growth hormone treatment for isolated growth hormone deficiency or childhood short stature: preliminary report of the French SAGhE study. J. Clin. Endocrinol. Metab. 97, 416–425 (2012)
Poidvin, A. et al. Growth hormone treatment for childhood short stature and risk of stroke in early adulthood. Neurology 83, 780–786 (2014)
Author information
Authors and Affiliations
Contributions
C.F. wrote the article. G.P.S. contributed to writing the article. J.H.C., M.S., A.P.G. and R.L. revised the manuscript and contributed to its content.
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Feeney, C., Scott, G., Cole, J. et al. Seeds of neuroendocrine doubt. Nature 535, E1–E2 (2016). https://doi.org/10.1038/nature18602
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/nature18602
This article is cited by
-
Transmission of amyloid-β protein pathology from cadaveric pituitary growth hormone
Nature (2018)
-
Iatrogenic Creutzfeldt-Jakob disease with Amyloid-β pathology: an international study
Acta Neuropathologica Communications (2018)
-
Amyloid-β accumulation in the CNS in human growth hormone recipients in the UK
Acta Neuropathologica (2017)
-
Collinge et al. reply
Nature (2016)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.