Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Microbiology

The dark side of antibiotics

Nature volume 534, pages 624–625 (2016)Cite this article

Subjects

Interactions in the gut between host cells and bacteria can determine a state of health or disease. A study investigates how antibiotic treatment can affect host cells in a way that drives growth of pathogenic bacteria. See Letter p.697

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Gut changes after antibiotic treatment.

Notes

  1. See all news & views

References

  1. Faber, F. et al. Nature 534, 697–699 (2016).

    Article  ADS  CAS  Google Scholar 

  2. Pavia, A. T. et al. J. Infect. Dis. 161, 255–260 (1990).

    Article  CAS  Google Scholar 

  3. Kelly, C. P., Pothoulakis, C. & LaMont, J. T. N. Engl. J. Med. 330, 257–262 (1994).

    Article  CAS  Google Scholar 

  4. Högenauer, C., Hammer, H. F., Krejs, G. J. & Reisinger, E. C. Clin. Infect. Dis. 27, 702–710 (1998).

    Article  Google Scholar 

  5. Bergogne-Bérézin, E. Int. J. Antimicrob. Agents 16, 521–526 (2000).

    Article  Google Scholar 

  6. Bohnhoff, M., Drake, B. L. & Miller, C. P. Proc. Soc. Exp. Biol. Med. 86, 132–137 (1954).

    Article  CAS  Google Scholar 

  7. Kofoid, E., Rappleye, C., Stojiljkovic, I. & Roth, J. J. Bacteriol. 181, 5317–5329 (1999).

    Article  CAS  Google Scholar 

  8. Garsin, D. A. Nature Rev. Microbiol. 8, 290–295 (2010).

    Article  CAS  Google Scholar 

  9. Thiennimitr, P. et al. Proc. Natl Acad. Sci. USA 108, 17480–17485 (2011).

    Article  ADS  CAS  Google Scholar 

  10. Ng, K. M. et al. Nature 502, 96–99 (2013).

    Article  ADS  CAS  Google Scholar 

  11. Songhet, P. et al. PLoS ONE 5, e13804 (2010).

    Article  ADS  Google Scholar 

  12. Lamichhane-Khadka, R., Benoit, S. L., Maier, S. E. & Maier, R. J. Open Biol. 3, 130146 (2013).

    Article  Google Scholar 

  13. Tackling Drug-Resistant Infections Globally: Final Report and Recommendations (Wellcome Trust/UK Gov., 2016).

Download references

Author information

Authors and Affiliations

  1. Thibault G. Sana and Denise M. Monack are in in the Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California 94305, USA.,

    Thibault G. Sana & Denise M. Monack

Authors
  1. Thibault G. Sana
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Denise M. Monack
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Thibault G. Sana or Denise M. Monack.

Related links

Related links

Related links in Nature Research

Microbiology: Antibiotics and adiposity

Nutrition: When guests turn hostile

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sana, T., Monack, D. The dark side of antibiotics. Nature 534, 624–625 (2016). https://doi.org/10.1038/nature18449

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nature18449

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing