The enzyme RNA polymerase II, along with several transcription factors, initiates DNA transcription. Analyses reveal the structures involved in this process in human and yeast cells at high-resolution. See Articles p.353 & p.359
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Hahn, S., Buratowski, S. Snapshots of transcription initiation. Nature 533, 331–332 (2016). https://doi.org/10.1038/nature18437
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DOI: https://doi.org/10.1038/nature18437