Extended Data Figure 5 : Base editing efficiencies of BE2 in U2OS and HEK293T cells.
From: Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
Cellular C to T conversion percentages by BE2 are shown for each of the six targeted genomic loci in HEK293T cells and U2OS cells. HEK293T cells were transfected using Lipofectamine 2000, and U2OS cells were nucleofected. Three days after plasmid delivery, genomic DNA was extracted and analysed for base editing at the six genomic loci by HTS. Values and error bars reflect the mean and standard deviation of two (U2OS) or three (HEK293T) biological experiments performed on different days.
