Extended Data Figure 9 : Genetic variants from ClinVar that, in principle, can be corrected by base editing.
From: Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
The NCBI ClinVar database of human genetic variations and their corresponding phenotypes (see main text ref. 4) was searched for genetic diseases that can be corrected by current base editing technologies. The results were filtered by imposing the successive restrictions listed on the left. The x axis shows the number of occurrences satisfying that restriction and all above restrictions on a logarithmic scale.
