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Depression

Ketamine steps out of the darkness

Nature volume 533, pages 477478 (26 May 2016) | Download Citation

The way in which ketamine exerts its antidepressant effects has been perplexing. Evidence that a metabolite of the drug is responsible, and acts on a different target from ketamine, might be the key to an answer. See Article p.481

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Affiliations

  1. Roberto Malinow is in the Department of Neurosciences, School of Medicine, and in the Section of Neurobiology, Division of Biology, University of California, San Diego, La Jolla, California 92093, USA.

    • Roberto Malinow

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Correspondence to Roberto Malinow.

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https://doi.org/10.1038/nature17897

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