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Regeneration

Limb regrowth takes two

Salamanders can regenerate several of their organs, including amputated limbs. Analysis of a Mexican salamander shows that crosstalk between two signalling molecules regulates limb regeneration. See Letter p.407

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Figure 1: Complementary signals promote limb regeneration.

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References

  1. 1

    Dinsmore, C. E. Int. J. Dev. Biol. 40, 621–627 (1996).

    CAS  PubMed  Google Scholar 

  2. 2

    Bryant, S. V. Nature 263, 676–679 (1976).

    ADS  CAS  Article  Google Scholar 

  3. 3

    Nacu, E., Gromberg, E., Oliveira, C., Drechsel, D. & Tanaka, E. M. Nature 533, 407–410 (2016).

    ADS  CAS  Article  Google Scholar 

  4. 4

    Nacu, E. & Tanaka, E. M. Annu. Rev. Cell Dev. Biol. 27, 409–440 (2011).

    CAS  Article  Google Scholar 

  5. 5

    Singer, M. Q. Rev. Biol. 27, 169–200 (1952).

    CAS  Article  Google Scholar 

  6. 6

    Lheureux, E. J. Embryol. Exp. Morphol. 38, 151–173 (1977).

    CAS  PubMed  Google Scholar 

  7. 7

    Meinhardt, H. J. Embryol. Exp. Morphol. 76, 115–137 (1983).

    CAS  PubMed  Google Scholar 

  8. 8

    Niswander, L., Jeffrey, S., Martin, G. R. & Tickle, C. Nature 371, 609–612 (1994).

    ADS  CAS  Article  Google Scholar 

  9. 9

    Zúñiga, A., Haramis, A.-P. G., McMahon, A. P. & Zeller, R. Nature 401, 598–602 (1999).

    ADS  Article  Google Scholar 

  10. 10

    Sugiura, T., Wang, H., Barsacchi, R., Simon, A. & Tanaka, E. M. Nature 531, 237–240 (2016).

    ADS  CAS  Article  Google Scholar 

Download references

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Correspondence to Miguel Torres.

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Torres, M. Limb regrowth takes two. Nature 533, 328–330 (2016). https://doi.org/10.1038/nature17889

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