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Cell biology

Ubiquitination without E1 and E2 enzymes

Nature volume 533, pages 43–44 (2016)Cite this article

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A protein in the pathogenic bacterium Legionella pneumophila has been found to attach the modifying molecule ubiquitin to human proteins, using a mechanism that, surprisingly, does not involve cellular E1 and E2 enzymes. See Letter p.120

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Figure 1: Mechanisms of ubiquitination.

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Authors and Affiliations

  1. Sagar Bhogaraju and Ivan Dikic are in the Institute of Biochemistry II, Goethe University School of Medicine, 60590 Frankfurt am Main, Germany, and in the Buchmann Institute for Molecular Life Sciences, Goethe University.,

    Sagar Bhogaraju & Ivan Dikic

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  1. Sagar Bhogaraju
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  2. Ivan Dikic
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Correspondence to Ivan Dikic.

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Bhogaraju, S., Dikic, I. Ubiquitination without E1 and E2 enzymes. Nature 533, 43–44 (2016). https://doi.org/10.1038/nature17888

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