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Structural biology

Antidepressants at work

Structures of the serotonin transporter protein SERT in complex with two different antidepressants shed light on how these drugs act, and point to possible targets for future drug development. See Article p.334

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Figure 1: Antidepressant blockade of a transporter protein.

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Correspondence to Marc G. Caron or Ulrik Gether.

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Caron, M., Gether, U. Antidepressants at work. Nature 532, 320–321 (2016). https://doi.org/10.1038/nature17883

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