Extended Data Figure 3 : Predicted probability of infection as a function of antibody levels.

From: A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges

Extended Data Figure 3

The per-challenge probability of infection was modelled as a function of antibody concentration at the time of each challenge using a probit regression model. The fitted probabilities from the models are plotted separately for each MAb group, with the estimated probability of infection for the control animals (0.27) indicated by the open circle adjacent to each ordinate. The VRC01 and VRC01-LS curves are superimposed. The points on each curve represent the median concentration at the time of breakthrough infection for each group of monkeys.