a, Bacterial numbers of wild-type B. abortus (strain 2308) recovered from in the spleen and placenta (n = 5 mice per group). b, c, Il6 mRNA expression (b) and total histopathology scores (c) in the placenta of mice at days 3, 7 and 13 after infection with B. abortus. d, Scoring criteria for blinded evaluation of haematoxylin and eosin (H&E)-stained sections from the placenta. e, Representative images of the histopathology observed in the placenta of B. abortus infected mice at days 3, 7 and 13 after infection. Arrow, neutrophil infiltration; N, necrosis.