Extended Data Figure 3 : Sex determination based on the number of sequences aligning to chromosome X and the autosomes.

From: Nuclear DNA sequences from the Middle Pleistocene Sima de los Huesos hominins

Extended Data Figure 3

Ninety-five per cent binomial confidence intervals are provided as well as the expected ratios of X to (X + autosomal) sequences for male and female samples. The analysis was performed with and without enrichment of endogenous DNA by filtering for the presence of C to T substitutions at terminal alignment positions. Present-day human contamination in the unfiltered sequences appears to have been introduced at least partly by female individuals.