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Molecular biology

Breaks in the brain

A high-throughput approach has found clusters of DNA double-strand breaks in neural cells. Most of the clusters are in large genes that are associated with neural function, which suggests that the breaks may have tissue-specific roles.

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Figure 1: Translocation hotspots.


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Correspondence to Thomas W. Glover or Thomas E. Wilson.

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Glover, T., Wilson, T. Breaks in the brain. Nature 532, 46–47 (2016).

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