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Epigenetics

An elusive DNA base in mammals

The discovery of a modified version of the base adenine, known as N6-methyladenine, in mouse DNA puts paid to the theory that cytosine derivatives are the only modified bases in mammals. See Article p.329

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Figure 1: Methyl modification in mammals.

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Correspondence to Gerd P. Pfeifer.

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Pfeifer, G. An elusive DNA base in mammals. Nature 532, 319–320 (2016). https://doi.org/10.1038/nature17315

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