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Cancer immunotherapy

Killers on sterols

Increasing cholesterol levels in the cell membranes of killer T cells boosts the cells' ability to mount an immune response against tumour cells in mice. Such a strategy might be valuable in anticancer immunotherapies. See Letter p.651

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Figure 1: Synergy at the immunological synapse.

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Correspondence to Michael L. Dustin.

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Dustin, M. Killers on sterols. Nature 531, 583–584 (2016). https://doi.org/10.1038/nature17310

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