Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Infection biology

Small RNA with a large impact

A simultaneous comparison of the RNA molecules expressed by Salmonella bacteria and human cells during infection reveals how a bacterial small RNA alters the transcript profiles of both the bacteria and the host cells. See Article p.496

This is a preview of subscription content

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.

Figure 1: PinT orchestrates gene expression in Salmonella and its host cells.


  1. 1.

    See all news & views


  1. 1

    Slauch, J. M., Mahan, M. J. & Mekalanos, J. J. Meth. Enzymol. 235, 481–492 (1994).

    CAS  Article  Google Scholar 

  2. 2

    Mandlik, A. et al. Cell Host Microbe 10, 165–174 (2011).

    CAS  Article  Google Scholar 

  3. 3

    Xiu, L. et al. Genet. Mol. Res. 14, 16948–16965 (2015).

    CAS  Article  Google Scholar 

  4. 4

    Westermann, A. J. et al. Nature 529, 496–501 (2016).

    ADS  CAS  Article  Google Scholar 

  5. 5

    Hautefort, I. et al. Cell. Microbiol. 10, 958–984 (2008).

    CAS  Article  Google Scholar 

  6. 6

    Wagner, E. G. H. & Romby, P. Adv. Genet. 90, 133–208 (2015).

    CAS  Article  Google Scholar 

  7. 7

    Uchiya, K. & Nikai, T. Infect Immun. 73, 5587–5594 (2005).

    CAS  Article  Google Scholar 

  8. 8

    Hannemann, S., Gao, B. & Galán, J. E. PLoS Pathog. 9, e1003668 (2013).

    Article  Google Scholar 

  9. 9

    Stecher, B. et al. PLoS Biol. 5, 2177–2189 (2007).

    CAS  Article  Google Scholar 

Download references

Author information



Corresponding authors

Correspondence to Matthias P. Machner or Gisela Storz.

Related links

Related links

Related links in Nature Research

Bacteriology: Toxins in tandem

Infection biology: Cheats never prosper

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Machner, M., Storz, G. Small RNA with a large impact. Nature 529, 472–473 (2016).

Download citation

Further reading


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing