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Neuroscience

A mechanism for myelin injury

The cells that insulate neuronal processes with a myelin membrane sheath are damaged during stroke. Data now show that an influx of calcium ions mediated by the TRPA1 protein contributes to myelin injury. See Letter p.523

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Figure 1: Myelin injury in a model of ischaemia.

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Correspondence to Aiman S. Saab or Klaus-Armin Nave.

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Saab, A., Nave, KA. A mechanism for myelin injury. Nature 529, 474–475 (2016). https://doi.org/10.1038/nature16865

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