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Palmer et al. reply

Nature volume 531, pages E2–E3 (2016)Cite this article

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replying to D. Chandler Nature 531, http://dx.doi.org/10.1038/nature16539 (2016)

We reported1 for the ST2 model of water advanced free energy calculations using six sampling techniques, all of which show the existence of a low-density liquid (LDL) as well as a high-density liquid (HDL) and a liquid–liquid phase transition (LLPT) between them. In the accompanying Comment2, Chandler contends that fundamental arguments3 preclude an LLPT in water and reiterates his claim4 that the LDL phase is an artefact associated with poor equilibration.

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References

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Author notes

  1. Jeremy C. Palmer & Yang Liu

    Present address: †Present addresses: Department of Chemical and Biomolecular Engineering, University of Houston, Houston, Texas 77204, USA (J.C.P.); Air Products and Chemicals, Inc., Allentown, Pennsylvania 18195, USA (Y.L.).,

Authors and Affiliations

  1. Department of Chemical and Biological Engineering, Princeton University, Princeton, New Jersey, 08544, USA

    Jeremy C. Palmer, Yang Liu, Athanassios Z. Panagiotopoulos & Pablo G. Debenedetti

  2. Department of Chemistry, Princeton University, Princeton, 08544, New Jersey, USA

    Fausto Martelli & Roberto Car

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Correspondence to Jeremy C. Palmer or Pablo G. Debenedetti.

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Palmer, J., Martelli, F., Liu, Y. et al. Palmer et al. reply. Nature 531, E2–E3 (2016). https://doi.org/10.1038/nature16540

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