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Cancer

Oncogene brought into the loop

Analysis of the 3D structure of DNA in tumour cells reveals how mutations in the IDH1 gene, and associated changes in methyl groups attached to DNA, elevate the expression of cancer-promoting genes. See Letter p.110

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Figure 1: Breaking down boundaries to cancer.

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Correspondence to Matthew R. Grimmer or Joseph F. Costello.

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J.F.C. is co-founder of Telo Therapeutics Inc.

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Grimmer, M., Costello, J. Oncogene brought into the loop. Nature 529, 34–35 (2016). https://doi.org/10.1038/nature16330

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