The protein IR25a is best known for its role as an odour receptor in flies, but an analysis reveals that it also acts to synchronize the circadian clock by sensing small temperature fluctuations. See Letter p.516
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References
Chen, C. et al. Nature 527, 516–520 (2015).
Wheeler, D. A., Hamblen-Coyle, M. J., Dushay, M. S. & Hall, J. C. J. Biol. Rhythms 8, 67–94 (1993).
Sehadova, H. et al. Neuron 64, 251–266 (2009).
Frank, D. D., Jouandet, G. C., Kearney, P. J., Macpherson, L. J. & Gallio, M. Nature 519, 358–361 (2015).
Liu, W. W., Mazor, O. & Wilson, R. I. Nature 519, 353–357 (2015).
Benton, R., Vannice, K. S., Gomez-Diaz, C. & Vosshall, L. B. Cell 136, 149–162 (2009).
Abuin, L. et al. Neuron 69, 44–60 (2011)
Picot, M., Klarsfeld, A., Chélot, E., Malpel, S. & Rouyer, F. J. Neurosci. 29, 8312–8320 (2009).
Kaneko, H. et al. Curr. Biol. 22, 1851–1857 (2012).
Wolfgang, W., Simoni, A., Gentile, C. & Stanewsky, R. Proc. R. Soc. B 280, 20130959 (2013).
Lee, Y. & Montell, C. J. Neurosci. 33, 6716–6725 (2013).
Das, A., Holmes, T. C. & Sheeba, V. PLoS ONE 10, e0134213 (2015).
Green, E. W. et al. Proc. Natl Acad. Sci. USA 112, 8702–8707 (2015).
Roessingh, S., Wolfgang, W. & Stanewsky, R. J. Biol. Rhythms http://dx.doi.org/10.1177/0748730415605633 (2015).
Brown, S. A., Zumbrunn, G., Fleury-Olela, F., Preitner, N. & Schibler, U. Curr. Biol. 12, 1574–1583 (2002).
Buhr, E. D., Yoo, S. H. & Takahashi, J. S. Science 330, 379–385 (2010).
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Rouyer, F., Chatterjee, A. A receptor for subtle temperature changes. Nature 527, 449–451 (2015). https://doi.org/10.1038/nature16316
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DOI: https://doi.org/10.1038/nature16316
