Extended Data Figure 3: Correction of gene expression after genetic rescue. | Nature

Extended Data Figure 3: Correction of gene expression after genetic rescue.

From: Reversal of phenotypes in MECP2 duplication mice using genetic rescue or antisense oligonucleotides

Extended Data Figure 3

a, b, RT–qPCR from the hypothalamus (a) and cerebellum (b) shows correction of altered expression of selected genes after normalization of MeCP2 levels in Flox;TG;Cre-TMX mice (n = 6 for Flox group; n = 7 for Flox;TG group; n = 7 for Flox;TG;Cre-vehicle group; n = 8 for Flox;TG;Cre-TMX group; two-tailed t-test). Data are mean ± s.e.m. *P < 0.05; **P < 0.01; ***P < 0.001.

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