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Molecular biology

DNA repair without flipping out

Time-resolved molecular snapshots of the bacterial enzyme AlkD reveal an unprecedented mechanism for the recognition and removal of damaged bases in DNA, with implications for cell biology and cancer therapy. See Letter p.254

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Figure 1: Two mechanisms for base excision.


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Correspondence to David S. Shin or John A. Tainer.

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Shin, D., Tainer, J. DNA repair without flipping out. Nature 527, 168–169 (2015).

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