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On the crest of becoming vertebrate

The discovery of cells in an invertebrate that share several features with vertebrate neural-crest cells provides insights into how this vital vertebrate cell population might have evolved. See Letter p.371

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Figure 1: Evolution of the neural crest.


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  1. Gans, C. & Northcuttt, R. G. Science 220, 268–273 (1983).

    ADS  CAS  Article  Google Scholar 

  2. Stolfi, A., Ryan, K., Meinertzhagen, I. A. & Christiaen, L. Nature 527, 371–374 (2015).

    ADS  CAS  Article  Google Scholar 

  3. Abitua, P. B., Wagner, E., Navarrete, I. A. & Levine, M. Nature 492, 104–107 (2012).

    ADS  CAS  Article  Google Scholar 

  4. Holland, L. Z. & Holland, N. D. Curr. Opin. Neurobiol. 9, 596–602 (1999).

    CAS  Article  Google Scholar 

  5. Yu, J.-K., Meulemans, D., McKeown, S. J. & Bronner-Fraser, M. Genome Res. 18, 1127–1132 (2008).

    CAS  Article  Google Scholar 

  6. Anderson, D. J. Neuron 3, 1–12 (1989).

    CAS  Article  Google Scholar 

  7. Green, S. A., Simoes-Costa, M. & Bronner, M. E. Nature 520, 474–482 (2015).

    ADS  CAS  Article  Google Scholar 

  8. Sansom, R. S., Gabbott, S. E. & Purnell, M. A. Nature 463, 797–800 (2010).

    ADS  CAS  Article  Google Scholar 

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Correspondence to Marianne E. Bronner.

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Bronner, M. On the crest of becoming vertebrate. Nature 527, 311–312 (2015).

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