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Non-coding RNA

Antibiotic tricks a switch

A screen for compounds that block a bacterial biosynthetic pathway has uncovered an antibiotic lead that shuts off pathogen growth by targeting a molecular switch in a regulatory RNA structure. See Article p.672

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Figure 1: Metabolic-pathway blockade identifies an antibiotic.

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Correspondence to Thomas Hermann.

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Hermann, T. Antibiotic tricks a switch. Nature 526, 650–651 (2015). https://doi.org/10.1038/nature15635

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