An ultra-high-resolution structure of the core segment of assembled α-synuclein — the protein that aggregates in the brains of patients with Parkinson's disease — has been determined. A neurobiologist and a structural biologist discuss the implications of this advance. See Article p.486
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a, Jose A. Rodriguez; b, Michael R. Sawaya
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Goedert, M., Cheng, Y. Crystals of a toxic core. Nature 525, 458–459 (2015). https://doi.org/10.1038/nature15630
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DOI: https://doi.org/10.1038/nature15630
