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Genetics

Location affects sporulation

Nature volume 525, pages 4243 (03 September 2015) | Download Citation

Monitored changes in the number of copies of a gene during DNA replication control the timing of sporulation in bacteria. This discovery links replication to the concept that a gene's location on a chromosome can influence cell traits.

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Author information

Affiliations

  1. Beth A. Lazazzera is in the Department of Microbiology, Immunology, and Molecular Genetics, University of California Los Angeles, Los Angeles, California 90095, USA.

    • Beth A. Lazazzera
  2. Diarmaid Hughes is in the Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala 751 23, Sweden.

    • Diarmaid Hughes

Authors

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Corresponding authors

Correspondence to Beth A. Lazazzera or Diarmaid Hughes.

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DOI

https://doi.org/10.1038/nature15207

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