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Genetics

Location affects sporulation

Monitored changes in the number of copies of a gene during DNA replication control the timing of sporulation in bacteria. This discovery links replication to the concept that a gene's location on a chromosome can influence cell traits.

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Figure 1: A genetic imbalance regulates sporulation.

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Correspondence to Beth A. Lazazzera or Diarmaid Hughes.

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Lazazzera, B., Hughes, D. Location affects sporulation. Nature 525, 42–43 (2015). https://doi.org/10.1038/nature15207

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