Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Computational biology

How to catch rare cell types

The development of an algorithm called RaceID enables the identification of rare cell types by single-cell RNA sequencing, even when they are part of a complex mixture of similar cells. See Letter p.251

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

Figure 1: Race to identify rare cells.

Notes

  1. 1.

    See all news & views

References

  1. 1

    Grün, D. et al. Nature 525, 251–255 (2015).

    ADS  Article  Google Scholar 

  2. 2

    Tang F., Lao, K. & Surani, M. A. Nature Methods 8, S6–S11 (2011).

    CAS  Article  Google Scholar 

  3. 3

    Eberwine, J., Sul, J. Y., Bartfai, T. & Kim, J. Nature Methods 11, 25–27 (2014).

    CAS  Article  Google Scholar 

  4. 4

    Treutlein, B. et al. Nature 509, 371–375 (2014).

    ADS  CAS  Article  Google Scholar 

  5. 5

    Klein, A. M. et al. Cell 161, 1187–1201 (2015).

    CAS  Article  Google Scholar 

  6. 6

    Macosko, E. Z. et al. Cell 161, 1202–1214 (2015).

    CAS  Article  Google Scholar 

  7. 7

    Stegle, O., Teichmann, S. A. & Marioni, J. C. Nature Rev. Genet. 16, 133–145 (2015).

    CAS  Article  Google Scholar 

  8. 8

    Clevers, H. Cell 154, 274–284 (2013).

    CAS  Article  Google Scholar 

  9. 9

    May, C. L. & Kaestner K. H. Mol. Cell. Endocrinol. 323, 70–75 (2010).

    CAS  Article  Google Scholar 

  10. 10

    Jaitin, D. A. et al. Science 343, 776–779 (2014).

    ADS  CAS  Article  Google Scholar 

Download references

Author information

Affiliations

Authors

Corresponding authors

Correspondence to Lu Wen or Fuchou Tang.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Wen, L., Tang, F. How to catch rare cell types. Nature 525, 197–198 (2015). https://doi.org/10.1038/nature15204

Download citation

Further reading

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing