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Cell biology

Tagged tags engage disposal

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Damaged organelles called mitochondria were once thought to be disposed of by a simple signalling cascade. Cell-based analyses now reveal that a network of complicated molecular interactions initiates disposal. See Article p.309

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Figure 1: The molecular mechanism of mitophagy.

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Correspondence to Noriyuki Matsuda or Keiji Tanaka.

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Matsuda, N., Tanaka, K. Tagged tags engage disposal. Nature 524, 294–295 (2015). https://doi.org/10.1038/nature15199

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