Extended Data Figure 5 : UK10K-cohorts, QQ plots.

From: The UK10K project identifies rare variants in health and disease

Extended Data Figure 5

QQ plots for the association tests of the 31 core traits in the WGS data set (n = 3,621 individuals). a, Single-variant analysis (˜14 million variants with MAF ≥ 0.1%); b, naive exome-wide Meta SKAT (1,783,548 variants with MAF < 1% in 50,717 windows); c, functional exome-wide Meta SKAT (LoF and missense; 256,733 variants with MAF < 1% in 14,909 windows); d, loss-of-function functional exome-wide Meta SKAT (LoF; 9,113 variants with MAF < 1% in 3,208 windows); e, genome-wide Meta SKAT (35,858,684 variants with MAF < 1% in 1,845,982 windows).