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DNA replication

Strand separation unravelled

The DNA double helix must be separated into single strands to be duplicated. A structure of the Mcm2–7 helicase enzyme responsible for this activity yields unprecedented insight into how the process is initiated. See Article p.186

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Figure 1: Structure of a strand separator.


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Correspondence to Matthew L. Bochman or Anthony Schwacha.

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Bochman, M., Schwacha, A. Strand separation unravelled. Nature 524, 166–167 (2015).

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