The DNA double helix must be separated into single strands to be duplicated. A structure of the Mcm2–7 helicase enzyme responsible for this activity yields unprecedented insight into how the process is initiated. See Article p.186
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Bochman, M., Schwacha, A. Strand separation unravelled. Nature 524, 166–167 (2015). https://doi.org/10.1038/nature14643
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DOI: https://doi.org/10.1038/nature14643
