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Molecular biology

It takes two to untangle

Nature volume 524, pages 169170 (13 August 2015) | Download Citation

Yeast require the enzyme Hsp104 to untangle protein aggregates, which arise in stressed or aged cells. Animals lack Hsp104, but it emerges that proteins of the DNAJ family of molecular chaperones can fulfil this role. See Letter p.251

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Affiliations

  1. Harm H. Kampinga is in the Department of Cell Biology, University Medical Center Groningen and University of Groningen, 9713 AV Groningen, the Netherlands.

    • Harm H. Kampinga

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Correspondence to Harm H. Kampinga.

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DOI

https://doi.org/10.1038/nature14640

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