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Structural biology

Arresting developments in receptor signalling

The first crystal structure of a G-protein-coupled receptor in complex with an arrestin protein provides insight into how the signalling pathways activated by these receptors are switched off through desensitization. See Article p.561

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Figure 1: The phototransduction pathway.

B, Parker DE Waal

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Correspondence to Jeffrey L. Benovic.

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Benovic, J. Arresting developments in receptor signalling. Nature 523, 538–539 (2015). https://doi.org/10.1038/nature14637

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