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Neurodegeneration

Aggregates feel the strain

Aggregates of α-synuclein protein can form in various cell types and cause different neurodegenerative disorders. The existence of strains with distinct structural conformations might explain this variability. See Letter p.340

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Figure 1: Structural variability and disease.

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Correspondence to Seung-Jae Lee or Eliezer Masliah.

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Lee, SJ., Masliah, E. Aggregates feel the strain. Nature 522, 296–297 (2015). https://doi.org/10.1038/nature14526

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