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Cancer

Antibodies regulate antitumour immunity

Boosting the T cells that mediate anticancer immune responses is a therapeutic goal. But T cells do not work alone — B cells and the antibodies they produce can both trigger and suppress the response. See Letters p.94 & p.99

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Figure 1: Two opposing roles for B cells in cancer immunology.

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Correspondence to Guido Kroemer.

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Zitvogel, L., Kroemer, G. Antibodies regulate antitumour immunity. Nature 521, 35–37 (2015). https://doi.org/10.1038/nature14388

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