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Plant biology

Coding in non-coding RNAs

The discovery of peptides encoded by what were thought to be non-coding – or 'junk' – regions of precursors to microRNA sequences reveals a new layer of gene regulation. These sequences may not be junk, after all. See Letter p.90

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Figure 1: MicroRNAs and their associated peptides.


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  1. Ameres, S. L. & Zamore, P. D. Nature Rev. Mol. Cell Biol. 14, 475–488 (2013).

    Article  CAS  Google Scholar 

  2. Lauressergues, D. et al. Nature 520, 90–93 (2015).

    Article  ADS  CAS  Google Scholar 

  3. Birney, E. et al. Nature 489, 57–74 (2012).

    Article  ADS  Google Scholar 

  4. Kellis, M. et al. Proc. Natl Acad. Sci. USA 111, 6131–6138 (2014).

    Article  ADS  CAS  Google Scholar 

  5. Carthew, R. W. & Sontheimer, E. J. Cell 136, 642–655 (2009).

    Article  CAS  Google Scholar 

  6. Fang, Y. & Spector, D. L. Curr. Biol. 17, 818–823 (2007).

    Article  CAS  Google Scholar 

  7. Zhang, L. et al. PLoS Genet. 5, e1000716 (2009).

    Article  Google Scholar 

  8. Cuperus, J. T., Fahlgren, N. & Carrington, J. C. Plant Cell 23, 431–442 (2011).

    Article  CAS  Google Scholar 

  9. Andrews, S. J. & Rothnagel, J. A. Nature Rev. Genet. 15, 193–204 (2014).

    Article  CAS  Google Scholar 

  10. Laing, W. A. et al. Plant Cell (2015).

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Correspondence to Peter M. Waterhouse.

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Waterhouse, P., Hellens, R. Coding in non-coding RNAs. Nature 520, 41–42 (2015).

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