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Structural biology

Calcium-activated proteins visualized

The first crystal structures of bestrophin and lipid scramblase proteins cast light on how these protein families transport very different substrates across membranes, yet are both activated by calcium ions. See Articles p.207 & p.213

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Figure 1: Cartoons of an activated lipid scramblase and a chloride channel.

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Correspondence to Matt Whorton.

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Whorton, M. Calcium-activated proteins visualized. Nature 516, 176–178 (2014). https://doi.org/10.1038/nature13944

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