Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Cell metabolism

Autophagy transcribed

Two studies find that an intracellular quality-control mechanism called autophagy is regulated by nuclear receptor proteins that govern the expression of autophagy genes. See Letters p.108 & p.112

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.

Figure 1: Regulation of starvation-induced autophagy.


  1. Rabinowitz, J. D. & White, E. Science 330, 1344–1348 (2010).

    Article  ADS  CAS  Google Scholar 

  2. Füllgrabe, J., Klionsky, D. J. & Joseph, B. Nature Rev. Mol. Cell Biol. 15, 65–74 (2014).

    Article  Google Scholar 

  3. Seok, S. et al. Nature 516, 108–111 (2014).

    Article  ADS  CAS  Google Scholar 

  4. Lee, J. M. et al. Nature 516, 112–115 (2014).

    Article  ADS  CAS  Google Scholar 

  5. Evans, R. M. & Mangelsdorf, D. J. Cell 157, 255–266 (2014).

    Article  CAS  Google Scholar 

  6. Settembre, C. et al. Science 332, 1429–1433 (2011).

    Article  ADS  CAS  Google Scholar 

  7. Settembre, C. et al. Nature Cell Biol. 15, 647–658 (2013).

    Article  CAS  Google Scholar 

  8. Settembre, C. et al. EMBO J. 31, 1095–1108 (2012).

    Article  CAS  Google Scholar 

  9. Sengupta, S., Peterson, T. R., Laplante, M., Oh, S. & Sabatini, D. M. Nature 468, 1100–1104 (2010).

    Article  ADS  CAS  Google Scholar 

  10. Singh, R. et al. Nature 458, 1131–1135 (2009).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations


Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Settembre, C., Ballabio, A. Autophagy transcribed. Nature 516, 40–41 (2014).

Download citation

  • Published:

  • Issue Date:

  • DOI:

This article is cited by


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing