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Towards unified vesicle endocytosis

An ultrafast, temperature-dependent mode of endocytosis, a process that is required for neurons to repeatedly fire, challenges current thinking and brings an old model back into the spotlight. See Article p.228

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Figure 1: Amalgamating endocytosis.


  1. Saheki, Y. & De Camilli, P. Cold Spring Harb. Perspect. Biol. 4, a005645 (2012).

    Article  Google Scholar 

  2. Watanabe, S. et al. Nature 515, 228–233 (2014).

    ADS  CAS  Article  Google Scholar 

  3. Miller, T. M. & Heuser, J. E. J. Cell Biol. 98, 685–698 (1984).

    CAS  Article  Google Scholar 

  4. Gaffield, M. A. & Betz, W. J. J. Neurosci. 27, 13691–13700 (2007).

    CAS  Article  Google Scholar 

  5. Micheva, K. D. & Smith, S. J. J. Neurosci. 25, 7481–7488 (2005).

    CAS  Article  Google Scholar 

  6. Renden, R. & von Gersdorff, H. J. Neurophysiol. 98, 3349–3359 (2007).

    Article  Google Scholar 

  7. Armbruster, M., Messa, M., Ferguson, S. M., De Camilli, P. & Ryan, T. A. eLife 2, e00845 (2013).

    Article  Google Scholar 

  8. Clayton, E. L. & Cousin, M. A. J. Neurochem. 111, 901–914 (2009).

    CAS  Article  Google Scholar 

  9. Rizzoli, S. O. & Jahn, R. Traffic 8, 1137–1144 (2007).

    CAS  Article  Google Scholar 

  10. Kononenko, N. L. et al. Neuron 82, 981–988 (2014).

    CAS  Article  Google Scholar 

  11. Wu, Y. et al. eLife 3, e01621 (2014).

    Article  Google Scholar 

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Correspondence to Vladan Lučić.

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Lučić, V. Towards unified vesicle endocytosis. Nature 515, 207–208 (2014).

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