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Lung disease

Treatment by cell transplant

Transplanting gene-corrected macrophage cells directly into the lungs of mice has been shown to effectively treat their pulmonary alveolar proteinosis, a hereditary lung disease also found in humans. See Article p.450

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Figure 1: Macrophage transplant corrects hereditary PAP in mice.


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Correspondence to Mary Jane Thomassen or Mani S. Kavuru.

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Thomassen, M., Kavuru, M. Treatment by cell transplant. Nature 514, 438–440 (2014).

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