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Structural biology

Lariat lessons

The spliceosome enzyme complex removes intron sequences from RNA transcripts to form messenger RNA. The crystal structure of a lasso-shaped RNA suggests a mechanism for this splicing process. See Article p.193

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Figure 1: Self-splicing reactions of group II introns.
Figure 2: Cartoon of the domain organization of group II introns.

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Correspondence to Robert T. Batey.

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Batey, R. Lariat lessons. Nature 514, 173–174 (2014). https://doi.org/10.1038/nature13754

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