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DNA repair

Making the cut

Analysis of the first step in repairing double-stranded-DNA breaks reveals that the Mre11 enzyme makes a DNA nick at a point separate from the break ends, creating an entry site for further processing by exonuclease enzymes. See Letter p.122

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Figure 1: Resection in the right direction.

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Correspondence to Lorraine S. Symington.

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Symington, L. Making the cut. Nature 514, 39–40 (2014). https://doi.org/10.1038/nature13751

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