Proteins are synthesized in cells by the ribosome apparatus. A report of 16 yeast ribosome structures, each bound by a different inhibitor, broadens our understanding of how drugs affect ribosome activity. See Article p.517
This is a preview of subscription content, access via your institution
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Prices vary by article type
Prices may be subject to local taxes which are calculated during checkout
Garreau de Loubresse, N. et al. Nature 513, 517–522 (2014).
Wilson, D. N. Crit. Rev. Biochem. Mol. Biol. 44, 393–433 (2009).
Wimberley, B. T. Curr. Opin. Invest. Drugs 10, 750–765 (2009).
Perez-Fernandez, D. et al. Nature Commun. 5, 3112; http://dx.doi.org/10.1038/ncomms4112 (2014).
Taguchi, A. et al. ChemMedChem http://dx.doi.org/10.1002/cmdc.201402208 (2014).
Schneider-Poetsch, T. et al. Nature Chem. Biol. 6, 209–217 (2010).
Schuwirth, B. S. et al. Science 310, 827–834 (2005).
Wong, W. et al. eLife 3, e03080 (2014).
Bai, X., Fernandez, I. S., McMullan, G. & Scheres, S. H. eLife 2, e00461 (2013).
About this article
Cite this article
Olivier, N. Ribosome revelations. Nature 513, 491–492 (2014). https://doi.org/10.1038/nature13747